Document Type : Original Article
Authors
1
Botany department, Faculty of science, Port said university, Port said, 42522 Egypt.
2
Botany Department, Faculty of Science, Port Said University, Port Said , 42522 Egypt.
3
Ear, Nose and Throat Department, Faculty of medicine, Mansoura University, Mansoura, 35516 Egypt.
4
Environmental Sciences Department, Faculty of Science, Port Said University, 42522 Egypt
Abstract
This work aims to evaluate the antifungal activity of commercial vinegar, apple cider vinegar, Eucalyptus oil and locasten ear drops in controlling otomycosis caused by Aspergillus niger. A total of 60 patients exhibiting otomycosis diagnosis were selected for fungal isolation. Fifty seven isolates were identified as Aspergillus niger. Different concentrations of an aqueous extractions of Eucalyptus leaves in addition to commercial vinegar, apple cider vinegar and locasten ear drops were applied to determine antifungal activity against Aspergillus niger. The antifungal activity was estimated as the decrease in the fungal dry weight. Activates of commercial vinegar, apple cider vinegar and Eucalyptus oil were also compared against commercial drug locasten ear drops. Results showed that by adding 1ml, 3ml and 5ml of tested substances at pH 6.0 and incubated at 35oc for 10 days exhibit antifungal activities against A. niger with more or less similar degrees. Also results showed that the addition of 5ml of commercial vinegar, apple cider, locasten ear drops and Eucalyptus oil resulted in inhibition percentage of 99.5%, 98.5%, 98.4% and 95.0% respectively. Furthermore the concentration of 1ml of locasten, commercial vinegar, apple cider and Eucalyptus oil resulted in inhibition percentage of 73.2%, 66.8%, 65.4% and 37.1% respectively. The highest inhibition activity ( 99.5% ) was caused by commercial vinegar solution at concentration of 5ml.
The authors recommended to apply commercial vinegar as a promising antifungal treatment for controlling otomycosis.
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