Evaluation of toxicity effects on tissues of kidney, heart, and chromosomes in vivo induced by sodium bicarbonate and the possible treatment by ethanolic extract solid dried tubers for Cyperus esculentus

Abd El-Aziz, Yasmin M.; Zaky, Heba K.; Khalaf, Aya E.; Hussien, Menna K.; Salah, Nayera G.; Mahmoud, Aya A.; Eldemery, Haidy M.; Abu Almaaty, Ali Hussein

doi:10.21608/ajbas.2022.147844.1111

Evaluation of toxicity effects on tissues of kidney, heart, and chromosomes in vivo induced by sodium bicarbonate and the possible treatment by ethanolic extract solid dried tubers for Cyperus esculentus

Document Type : Original Article

Authors

¹ Zoology Department, Faculty of Science, Port Said University, Port Said, Egypt.

² Zoology Department, Faculty of Science, Port Said University, Port Said, Egypt

³ Zoology Department, Faculty of Science, Port-Said University, Egypt.

⁴ Zoology Department, Faculty of Science, Port Said University

10.21608/ajbas.2022.147844.1111

Abstract

Many fields exist in using rats in the experiment on different materials that have the desired result for the benefit of mankind. The rat is used in laboratories to perform experiments for various sciences such as physiology, pharmacology, cardiology, toxicology, neurosciences, and others. This is since small rodents in size, their life cycle is short, and their genetic traits are numerous, so the desired results appear in short times that do not reach several years like the rest of the animals. Also, the rodents are easy to rise if we provide a comprehensive environment to ensure their continuity. We used sodium bicarbonate in our experiment because of its frequent use today. It should be noted that sodium bicarbonate is considered a dangerous substance because it causes a marked increase in the volume of fluid in the vessels, which leads to acute pulmonary edema. Cyperus esculentus or what is known as (Tiger nut) to treat rats, as it is useful and contains some anti-inflammatory. It is used as a heart tonic and has an effective ability to treat diarrhea, and it also reduces colon cancer disorder.

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